PHISTO: Pathogen-host interaction search tool

Durmuş Tekir S., Çakir T., Ardiç E., Sayilirbaş A. S., Konuk G., Konuk M., ...More

Bioinformatics, vol.29, no.10, pp.1357-1358, 2013 (SCI-Expanded, Scopus) identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 10
  • Publication Date: 2013
  • Doi Number: 10.1093/bioinformatics/btt137
  • Journal Name: Bioinformatics
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1357-1358
  • Galatasaray University Affiliated: No

Abstract

Knowledge of pathogen-host protein interactions is required to better understand infection mechanisms. The pathogen-host interaction search tool (PHISTO) is a web-accessible platform that provides relevant information about pathogen-host interactions (PHIs). It enables access to the most up-to-date PHI data for all pathogen types for which experimentally verified protein interactions with human are available. The platform also offers integrated tools for visualization of PHI networks, graph-theoretical analysis of targeted human proteins, BLAST search and text mining for detecting missing experimental methods. PHISTO will facilitate PHI studies that provide potential therapeutic targets for infectious diseases. © 2013 The Author. Published by Oxford University Press. All rights reserved.