PHISTO: Pathogen-host interaction search tool

Durmuş Tekir S., Çakir T., Ardiç E., Sayilirbaş A. S., Konuk G., Konuk M., ...Daha Fazla

Bioinformatics, cilt.29, sa.10, ss.1357-1358, 2013 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 29 Sayı: 10
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1093/bioinformatics/btt137
  • Dergi Adı: Bioinformatics
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1357-1358
  • Galatasaray Üniversitesi Adresli: Hayır

Özet

Knowledge of pathogen-host protein interactions is required to better understand infection mechanisms. The pathogen-host interaction search tool (PHISTO) is a web-accessible platform that provides relevant information about pathogen-host interactions (PHIs). It enables access to the most up-to-date PHI data for all pathogen types for which experimentally verified protein interactions with human are available. The platform also offers integrated tools for visualization of PHI networks, graph-theoretical analysis of targeted human proteins, BLAST search and text mining for detecting missing experimental methods. PHISTO will facilitate PHI studies that provide potential therapeutic targets for infectious diseases. © 2013 The Author. Published by Oxford University Press. All rights reserved.