Finance capitalism, which comes to existence more rapidly and in a more complex way than other modes of production, has brought about significant changes in the nature of the relationship between human beings and nature. Our information society not only functionalizes technology as an instrument, but also renders it a determinant framework in both material and intellectual terms. Professions such as medicine and aviation, which deal with vital issues and are obliged to adapt themselves to technological innovations by their very nature, function as a road map enabling us to track this transformation. We conducted a field study between 2015 and 2017 and we interviewed 25 physicians and 27 pilots using a semi-structured interview technique. We conducted this field study to comprehend how this technology-centered approach transforms pilotage and medicine, two professions that are directly influenced by the results of technological invasion, in terms of their social meaning and professional values such as mastery and skill inherent to them. Based on the findings of this research, our article aims to develop a conceptualization that has the potential to help us better understand social transformations starting from the position of professions vis-a-vis technology and the transformation that they underwent in terms of their performance and mastery practice.